Madison Pearce

About me

Originally, I come from Bristol (United Kingdom) but moved to Oxford for my undergraduate degree in 2011. I was accepted to Hertford College by Martin Maiden as an undergraduate student and have been working with him since. My passion for molecular epidemiology was first realised, when I undertook my third year undergraduate research product with this lab group, in conjunction with Public Health England (PHE). I completed my undergraduate degree in 2014 and was  offered a DPhil position in the group. I am now a second year DPhil student, specialising in Salmonella enterica. I continue to work in conjunction with PHE, as I am funded by the Health Protection Research Unit (HPRU), Gastrointestinal Pathogens as part of the National Institute for Health Research. This funding body was established to work in conjunction with leading institutions to create academic posts which specalise in public health research developments. I have presented or had work presented at multiple conferences including: HPRU Gastrointestinal Annual General Meeting; the International Meeting on Microbial Epidemiological Markers and the PHE Applied Epidemiology Conference.

Research interests

During my undergraduate degree I developed interests in: disease, bacteria, molecular biology, genetics and phylogenetics. All of these areas contributed to my current research interests within S. enterica. In particular, I am interested in outbreak analyses and the development of novel methods for detection, identification, typing and analysis of outbreaks. This research ties into more general interests in the typing and classification of isolates. I have been responsible for the creation of the ribosomal MultiLocus Typing Scheme (rMLST) within Salmonella and have been working on examining the similarities and differences between classical antigenic serovar typing of Salmonella and newer genetic based methods. My interest in typing of Salmonella has led to the creation of a preliminary core genome scheme, which contains genes present in all Salmonella isolates. Finally, I am interested in compatibility between typing schemes and analytical approaches and as such spend time doing cross validation on varying methodologies.